Archer’s annual STEM Symposium is an opportunity for Los Angeles high school students who have completed independent or small group projects in STEM to present their findings. Students are invited to present their research in the fields of molecular biology, chemistry, physics, and engineering.

The Archer RISE Award honors exceptional young women for their innovative scientific research or engineering design projects that further existing knowledge or develop solutions to pressing scientific challenges. Finalists for the RISE Award are noted in throughout the online program and will be awarded at lunch on May 21.

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Saturday, May 21 • 9:15am - 10:30am
Glowing Bacteria: Lighting the Path to New Antibiotics

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Bacteria modify their behavior according to their population density using a cell-cell communication system called quorum sensing, which Vibrio harveyi uses to produce bioluminescence. In my project, a range of concentrations of three safe plant extracts that are known to have quorum sensing inhibitory properties were added to samples of Vibrio harveyi to learn about toxicity and the extent of change in the bioluminescence as a function of concentration. I predicted the effect of the substances to exponentially decrease the bioluminescence of the bacteria according to concentration. Quorum sensing is involved in so many bacterial behaviors that control of the system can pose solutions to many problems. Specifically, virulent bacteria use quorum sensing to activate their pathogenicity, so this type of research could eventually be used as a new form of antibiotic since current medicine is producing antibiotic resistant bacteria.


Kelly Fradet

Flintridge Sacred Heart Academy
Flintridge Sacred Heart Academy; Grade 12

Saturday May 21, 2016 9:15am - 10:30am
Dining Hall